Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4599210 | 0.85 | ALDH1A1 (0.48) | LMNAALOX5CES2CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL8805740 | 0.84 | MAPK1 (0.48) | LMNAALOX5CES2CYP1A2CYP3A4 | |
| SCHEMBL8806746 | 0.81 | L3MBTL1 (0.39) | LMNAL3MBTL1ALOX5CYP1A2CYP3A4 | |
| SCHEMBL29158505 | 0.77 | ALDH1A1 (0.55) | LMNAALOX5CES2CYP1A2CYP3A4 | |
| SCHEMBL9719389 | 0.76 | LMNA (0.44) | LMNAALOX5CYP1A2CYP3A4GAA | |
| SCHEMBL8805922 | 0.76 | LMNA (0.39) | LMNAL3MBTL1ALOX5CYP1A2CYP3A4 | |
| SCHEMBL4687956 | 0.75 | ALOX5 (0.50) | ALOX5CES2CYP1A2CYP3A4GAA | |
| SCHEMBL9719342 | 0.74 | ALOX5 (0.47) | LMNAL3MBTL1ALOX5CYP11B1CYP11B2 | |
| SCHEMBL12203852 | 0.73 | OPRM1 (0.46) | ALOX5CES2GAAOPRM1OPRK1 | |
| SCHEMBL27632123 | 0.72 | L3MBTL1 (0.46) | LMNAL3MBTL1GAAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000760-A1 | METHOD OF TREATING NEUROLOGICAL DYSFUNCTION USING NEUROTRANSMITTER ENHANCES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-01-23 | — | — | WO | disclosed |