Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720872 | 0.88 | VSIR (0.45) | SMN1; SMN2MAPTVSIRMEN1KMT2A | |
| SCHEMBL9720698 | 0.82 | GRIN2B (0.41) | SMN1; SMN2MAPTVSIRTNKSPARP1 | |
| SCHEMBL9720791 | 0.80 | SMPD3 (0.40) | VSIRMEN1KMT2ATNKSPARP1 | |
| SCHEMBL9720663 | 0.78 | HRH4 (0.44) | SMN1; SMN2VSIRMEN1KMT2A | |
| SCHEMBL9720691 | 0.76 | NPSR1 (0.40) | MAPTMEN1KMT2AMMP2MMP9 | |
| SCHEMBL8973605 | 0.74 | PIN1 (0.46) | SMN1; SMN2GAAMAPTMEN1KMT2A | |
| SCHEMBL9720685 | 0.72 | KDM4E (0.39) | SMN1; SMN2GAAMAPTMEN1KMT2A | |
| SCHEMBL27071533 | 0.72 | GAA (0.74) | SMN1; SMN2GAAMAPTMEN1KMT2A | |
| SCHEMBL19245652 | 0.72 | GAA (0.74) | SMN1; SMN2GAAMAPTMEN1KMT2A | |
| SCHEMBL8963868 | 0.72 | DRD2 (0.63) | SMN1; SMN2MAPTDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142052-A | Cationic effect-driven carbinol/amine reaction | LABORATOIRES SYNTEX (FR) | 1992-08-25 | — | — | US | disclosed |