Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | CNR1 | P21554 | 2/20 | 0.61 |
| ▸ | HRH1 | P35367 | 2/20 | 0.61 |
| ▸ | GHSR | Q92847 | 2/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HPN | P05981 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720741 | 0.85 | OPRD1 (0.55) | KCNH2OPRK1CYP3A4ADORA3CNR1 | |
| SCHEMBL9720680 | 0.84 | SIGMAR1 (0.54) | CYP3A4USP2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9720704 | 0.84 | OPRD1 (0.69) | KCNH2OPRK1CYP3A4ADORA3CNR1 | |
| SCHEMBL9720683 | 0.83 | ATM (0.54) | KCNH2OPRK1CYP3A4ADORA3CNR1 | |
| Belarizine SCHEMBL2108057 | 0.83 | ATM (0.73) | KCNH2OPRK1CYP3A4ADORA3CNR1 | |
| SCHEMBL29599947 | 0.80 | CYP3A4 (0.85) | KCNH2OPRK1CYP3A4ADORA3CNR1 | |
| SCHEMBL16226762 | 0.80 | CYP3A4 (0.85) | KCNH2OPRK1CYP3A4ADORA3CNR1 | |
| SCHEMBL16226272 | 0.77 | LMNA (0.70) | KCNH2OPRK1CYP3A4ADORA3CNR1 | |
| SCHEMBL9720751 | 0.77 | KCNH2 (0.71) | KCNH2OPRK1CYP3A4ADORA3CNR1 | |
| SCHEMBL17942918 | 0.76 | CYP3A4 (0.84) | KCNH2OPRK1CYP3A4ADORA3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142052-A | Cationic effect-driven carbinol/amine reaction | LABORATOIRES SYNTEX (FR) | 1992-08-25 | — | — | US | disclosed |