Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720800 | 0.85 | SIGMAR1 (0.56) | SIGMAR1OPRD1SMN1; SMN2ATMHTT | |
| SCHEMBL9720767 | 0.84 | KCNH2 (0.61) | OPRD1SMN1; SMN2KDM4EALDH1A1ATM | |
| SCHEMBL9720741 | 0.82 | OPRD1 (0.55) | SIGMAR1OPRD1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9720704 | 0.81 | OPRD1 (0.69) | OPRD1SMN1; SMN2ATMMEN1KMT2A | |
| Belarizine SCHEMBL2108057 | 0.80 | ATM (0.73) | OPRD1KDM4EALDH1A1ATMHTT | |
| SCHEMBL9720646 | 0.76 | ALDH1A1 (0.54) | SIGMAR1OPRD1KDM4EALDH1A1ATM | |
| SCHEMBL9720683 | 0.75 | ATM (0.54) | OPRD1SMN1; SMN2ALDH1A1ATMMEN1 | |
| SCHEMBL9720751 | 0.74 | KCNH2 (0.71) | SIGMAR1OPRD1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1569388 | 0.74 | KCNH2 (0.70) | SIGMAR1SMN1; SMN2KDM4EALDH1A1ATM | |
| SCHEMBL9720786 | 0.73 | ATM (0.59) | OPRD1SMN1; SMN2ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142052-A | Cationic effect-driven carbinol/amine reaction | LABORATOIRES SYNTEX (FR) | 1992-08-25 | — | — | US | disclosed |