Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.31 |
| ▸ | BCL2 | P10415 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721245 | 0.84 | MAPT (0.41) | BCL2L1KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL9721291 | 0.83 | TLR8 (0.36) | TLR8CA1CA2HSD17B1HSD17B2 | |
| SCHEMBL9721418 | 0.82 | CA1 (0.36) | TLR8CA1CA2HSD17B1HSD17B2 | |
| SCHEMBL9721311 | 0.79 | MAOA (0.36) | TLR8ESR1ESR2CYP3A4PIM1 | |
| SCHEMBL9721297 | 0.78 | CA1 (0.43) | TLR8CA1CA2HSD17B1HSD17B2 | |
| SCHEMBL29006355 | 0.74 | ESR2 (0.41) | CA1CA2HSD17B1HSD17B2ESR1 | |
| SCHEMBL24923348 | 0.64 | SELL (0.40) | CA1CA2BCL2L1BCL2MCL1 | |
| SCHEMBL24936683 | 0.64 | SELL (0.40) | CA1CA2BCL2L1BCL2MCL1 | |
| SCHEMBL9721339 | 0.63 | TLR8 (0.51) | TLR8HSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL922255 | 0.62 | CA1 (0.56) | CA1CA2ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112869-A | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-05-12 | — | — | US | claimed |