Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL9723512 | 0.93 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1LMNASCN5ASCN9A | |
| SCHEMBL9723459 | 0.85 | GRIN2D (0.39) | — | |
| SCHEMBL9723422 | 0.82 | LMNA (0.45) | HSP90AA1LMNATDP1 | |
| SCHEMBL9723569 | 0.79 | — | — | |
| SCHEMBL9723545 | 0.77 | NPSR1 (0.47) | LMNAGABRA1GABRG2GABRB3HPGD | |
| SCHEMBL9723469 | 0.76 | LMNA (0.40) | LMNA | |
| SCHEMBL9723522 | 0.74 | KMT2A (0.49) | LMNASMN1; SMN2TDP1NLRP3 | |
| SCHEMBL19368005 | 0.72 | GABRA1 (0.46) | LMNAGABRA1GABRG2GABRB3SMN1; SMN2 | |
| SCHEMBL9723449 | 0.72 | KMT2A (0.43) | SMN1; SMN2CYP1A2TSHRALOX5 | |
| Diphenylamine SCHEMBL9723489 | 0.71 | NPSR1 (0.40) | LMNAHPGDCA1CA2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153223-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | claimed |