Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20540474 | 0.77 | KMT2A (0.57) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL8819876 | 0.77 | KMT2A (0.61) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL9723449 | 0.76 | KMT2A (0.43) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7565089 | 0.75 | LMNA (0.48) | KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9723571 | 0.74 | HSP90AA1 (0.40) | LMNASMN1; SMN2TDP1NLRP3 | |
| SCHEMBL9678852 | 0.74 | KMT2A (0.57) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL9678861 | 0.74 | KMT2A (0.57) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL9723545 | 0.73 | NPSR1 (0.47) | KMT2ALMNA | |
| SCHEMBL6429941 | 0.73 | KMT2A (0.65) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL462304 | 0.73 | LPAR1 (0.66) | KMT2ALMNASMN1; SMN2MEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153223-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | claimed |