Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylamine SCHEMBL9723489 | 0.92 | NPSR1 (0.40) | NPSR1ALOX5LMNAKMT2AAPAF1 | |
| SCHEMBL9723422 | 0.78 | LMNA (0.45) | LMNAKMT2A | |
| SCHEMBL27692421 | 0.78 | NPSR1 (0.64) | NPSR1ALOX5KMT2AAPAF1NPC1 | |
| SCHEMBL9723571 | 0.77 | HSP90AA1 (0.40) | ALOX5LMNACA1CA2GABRA1 | |
| SCHEMBL9723449 | 0.73 | KMT2A (0.43) | ALOX5KMT2AALDH1A1CYP1A2TSHR | |
| SCHEMBL9680283 | 0.73 | ALDH1A1 (0.62) | NPSR1LMNAKMT2ANPC1ALDH1A1 | |
| SCHEMBL9723522 | 0.73 | KMT2A (0.49) | LMNAKMT2A | |
| SCHEMBL9723459 | 0.72 | GRIN2D (0.39) | — | |
| SCHEMBL9723469 | 0.72 | LMNA (0.40) | NPSR1LMNAKMT2A | |
| SCHEMBL7909023 | 0.72 | GABRA1 (0.43) | ALOX5LMNAKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153223-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | claimed |