Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723545 | 0.92 | NPSR1 (0.47) | NPSR1KMT2AALDH1A1LMNACA12 | |
| SCHEMBL9723422 | 0.72 | LMNA (0.45) | KMT2AMEN1LMNATDP1 | |
| SCHEMBL27692421 | 0.72 | NPSR1 (0.64) | NPSR1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL9723571 | 0.71 | HSP90AA1 (0.40) | LMNACA12CA1CA2CA9 | |
| SCHEMBL9723449 | 0.70 | KMT2A (0.43) | MAPTKMT2AALDH1A1MEN1ALOX5 | |
| SCHEMBL9723522 | 0.70 | KMT2A (0.49) | KMT2AMEN1LMNATDP1 | |
| SCHEMBL9723469 | 0.69 | LMNA (0.40) | NPSR1KMT2AMEN1GAALMNA | |
| Diethylamine SCHEMBL9723512 | 0.68 | HSP90AA1 (0.36) | LMNACA12CA1CA2CA9 | |
| SCHEMBL9680283 | 0.67 | ALDH1A1 (0.62) | NPSR1MAPTKMT2AALDH1A1MEN1 | |
| Diphenylamine SCHEMBL10650342 | 0.67 | NPSR1 (0.54) | NPSR1MAPTKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153223-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |