Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934932 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MAPTTSHRNPSR1GLO1 | |
| SCHEMBL22342678 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPTTSHRNPSR1GLO1 | |
| SCHEMBL20283670 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MAPTTSHRNPSR1GLO1 | |
| SCHEMBL166879 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTTSHRNPSR1GLO1 | |
| SCHEMBL79588 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTTSHRNPSR1GLO1 | |
| SCHEMBL13269637 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTTSHRNPSR1GLO1 | |
| SCHEMBL28293945 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTTSHRNPSR1GLO1 | |
| SCHEMBL19687702 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTTSHRNPSR1GLO1 | |
| SCHEMBL14010565 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTTSHRNPSR1GLO1 | |
| SCHEMBL13502864 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTTSHRNPSR1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355789-A1 | POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2017-12-14 | — | — | US | disclosed |
| US-20170355789-A1 | POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2017-12-14 | — | — | US | disclosed |
| US-20170073438-A1 | POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2017-03-16 | — | — | US | disclosed |
| US-20170073438-A1 | POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2017-03-16 | — | — | US | disclosed |
| US-9527795-B2 | Methylene beta-ketoester monomers, methods for making methylene beta-ketoester monomers, polymerizable compositions and products formed therefrom | SIRRUS, INC. (US) | 2016-12-27 | — | — | US | disclosed |
| US-9527795-B2 | Methylene beta-ketoester monomers, methods for making methylene beta-ketoester monomers, polymerizable compositions and products formed therefrom | SIRRUS, INC. (US) | 2016-12-27 | — | — | US | disclosed |
| US-9173395-B2 | Use of substituted isoquinolinones, isoquinolindiones, isoquinolintriones and dihydroisoquinolinones or in each case salts thereof as active agents against abiotic stress in plants | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-03 | — | — | US | disclosed |
| US-20140302987-A1 | USE OF SUBSTITUTED ISOQUINOLINONES, ISOQUINOLINDIONES, ISOQUINOLINTRIONES AND DIHYDROISOQUINOLINONES OR IN EACH CASE SALTS THEREOF AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-09 | — | — | US | disclosed |
| US-20140288230-A1 | METHYLENE BETA-KETOESTER MONOMERS, METHODS FOR MAKING METHYLENE BETA-KETOESTER MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2014-09-25 | — | — | US | disclosed |
| US-20140288230-A1 | METHYLENE BETA-KETOESTER MONOMERS, METHODS FOR MAKING METHYLENE BETA-KETOESTER MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2014-09-25 | — | — | US | disclosed |
| US-5089504-A | SUBSTITUTED 4-AMINOQUINOLINE DERIVATIVES AS GASTRIC ACID SECRETION INHIBITORS | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288230-A1 | METHYLENE BETA-KETOESTER MONOMERS, METHODS FOR MAKING METHYLENE BETA-KETOESTER MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | MACF1, MSMO1, ILK | ALDH1A1 1292/4885MAPT 1280/4885TSHR 4869/4885 |
| US-20140302987-A1 | USE OF SUBSTITUTED ISOQUINOLINONES, ISOQUINOLINDIONES, ISOQUINOLINTRIONES AND DIHYDROISOQUINOLINONES OR IN EACH CASE SALTS THEREOF AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS | NQO1, NFE2, NDUFS1 | ALDH1A1 728/4885MAPT 3346/4885TSHR 4501/4885 |
| US-20170355789-A1 | POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM | BHMT2, BHMT, MACF1 | ALDH1A1 562/4885MAPT 980/4885TSHR 4885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.