Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30997420 | 1.00 | CA5A (0.47) | CA5AGAATRPV4CYP3A4L3MBTL1 | |
| SCHEMBL9724436 | 0.88 | CA5A (0.61) | CA5AGAATRPV4L3MBTL1TSHR | |
| SCHEMBL2915192 | 0.87 | GAA (0.47) | CA5AGAATRPV4CYP3A4L3MBTL1 | |
| SCHEMBL30610782 | 0.85 | PKM (0.57) | CA5AGAACYP3A4L3MBTL1TSHR | |
| SCHEMBL48765 | 0.85 | PKM (0.57) | CA5AGAACYP3A4L3MBTL1TSHR | |
| SCHEMBL9633696 | 0.83 | SMN1; SMN2 (0.60) | GAAL3MBTL1ALDH1A1MAPTPKM | |
| SCHEMBL9125107 | 0.82 | CA5A (0.48) | CA5AGAAL3MBTL1TSHRALDH1A1 | |
| SCHEMBL741235 | 0.81 | ALPL (0.51) | TRPV4L3MBTL1TSHRHTTSMN1; SMN2 | |
| SCHEMBL9632442 | 0.80 | TSHR (0.60) | CA5AGAACYP3A4TSHRALDH1A1 | |
| SCHEMBL30792215 | 0.80 | GSTO1 (0.41) | L3MBTL1TSHRALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221610-A | Phenylthiazole amine PI4KIII beta/HDAC double-target inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-06-21 | — | — | CN | disclosed |
| US-20220153711-A1 | P14-Kinase Inhibitors and Methods of Using the Same | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2022-05-19 | — | — | US | disclosed |
| US-20220017507-A1 | PI-Kinase Inhibitors with Anti-Infective Activity | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-01-20 | — | — | US | disclosed |
| US-11091472-B2 | PI-kinase inhibitors with anti-infective activity | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-17 | — | — | US | disclosed |
| WO-2020191205-A1 | PI4-KINASE INHIBITORS AND METHODS OF USING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-09-24 | — | — | WO | disclosed |
| WO-2017147526-A1 | PI-KINASE INHIBITORS WITH ANTI-INFECTIVE ACTIVITY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-08-31 | — | — | WO | disclosed |
| EP-1444199-B1 | RACEMIC TAMSULOSIN FREE BASE AND METHODS OF MAKING THE SAME | SYNTHON BV (NL) | 2008-12-17 | — | — | EP | disclosed |
| EP-1905758-A1 | Tamsulosin free base and recovery process thereof | Synthon B.V. (NL) | 2008-04-02 | — | — | EP | disclosed |
| US-6965051-B2 | Process for resolution of tamsulosin and compounds, compositions, and processes associated therewith | SYNTHON IP INC. (US) | 2005-11-15 | — | — | US | disclosed |
| US-20050096394-A1 | Process for resolution of tamsulosin and compounds, compositions, and processes associated therewith | HOORN HANS J (NL) | 2005-05-05 | — | — | US | disclosed |
| US-4987152-A | ADRENERGIC BLOCKING AGENTS, HYPOTENSIVES, CONGESTIVE HEART FAILURE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4880841-A | ADRENERGIC BLOCKING AGENTS, HYPOTENSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| US-4868216-A | ANTIADRENERGIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-19 | — | — | US | disclosed |
| US-4761500-A | CONGESTIVE HEART FAILURE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-08-02 | — | — | US | disclosed |
| US-4731478-A | ADRENERGIC BLOCKING AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-03-15 | — | — | US | disclosed |
| US-4703063-A | TAMSULOSIN HYDROCHLORIDE; antihypertensive agent and an agent for the treatment of congestive heart failure | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1987-10-27 | — | — | US | disclosed |
| US-4558156-A | ADRENERGIC BLOCKING AGENT, HYPOTENSIVE AGENT | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-12-10 | — | — | US | disclosed |
| EP-0034432-B1 | SULFAMOYL-SUBSTITUTED PHENETHYLAMINE DERIVATIVES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS, CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1984-04-25 | — | — | EP | disclosed |
| US-4373106-A | Sulfamoyl-substituted phenethylamine derivatives and process of producing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-02-08 | — | — | US | disclosed |
| EP-0034432-A2 | Sulfamoyl-substituted phenethylamine derivatives, their preparation, and pharmaceutical compositions, containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-08-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096394-A1 | Process for resolution of tamsulosin and compounds, compositions, and processes associated therewith | REN, ADRB1, ARRB1 | CA5A 2448/4885GAA 1760/4885TRPV4 643/4885 |
| US-11091472-B2 | PI-kinase inhibitors with anti-infective activity | PIP4K2A, PIP5K1A, PIP4K2C | CA5A 3855/4885GAA 2220/4885TRPV4 2367/4885 |
| US-20220153711-A1 | P14-Kinase Inhibitors and Methods of Using the Same | PI4KB, PI4KA, PI4K2A | CA5A 3867/4885GAA 3114/4885TRPV4 3066/4885 |
| US-20220017507-A1 | PI-Kinase Inhibitors with Anti-Infective Activity | PIP4K2A, PIP5K1A, PIP4K2C | CA5A 3826/4885GAA 1912/4885TRPV4 2270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.