Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724808 | 0.89 | MEN1 (0.53) | KMT2AMEN1GAAATMNPC1 | |
| SCHEMBL9724829 | 0.86 | BACE1 (0.54) | KMT2AMEN1GAANPC1RAB9A | |
| SCHEMBL9724967 | 0.85 | MAPT (0.67) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9724923 | 0.85 | RAB9A (0.50) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5037571 | 0.85 | MAPK1 (0.63) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2610069 | 0.83 | KMT2A (0.54) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL6663334 | 0.82 | ROCK2 (0.60) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL2610082 | 0.82 | MEN1 (0.74) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL21880195 | 0.82 | ROCK2 (0.60) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL10176502 | 0.82 | ROCK2 (0.60) | KMT2AMEN1GAAATMGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |