Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | PPIA | P62937 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724808 | 0.86 | MEN1 (0.53) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL9724970 | 0.86 | MAPT (0.55) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL9724978 | 0.85 | KMT2A (0.52) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL9724786 | 0.84 | DDX3X (0.51) | MAPTTP53RAB9AMEN1KMT2A | |
| SCHEMBL28556649 | 0.84 | MAPT (0.65) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL28556648 | 0.84 | MAPT (0.65) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL9724958 | 0.82 | MAPT (0.62) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL9724859 | 0.81 | ALDH1A1 (0.60) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL9724920 | 0.81 | RAB9A (0.67) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9724829 | 0.78 | BACE1 (0.54) | MAPTTP53NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |