Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724808 | 0.89 | MEN1 (0.53) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL9724829 | 0.86 | BACE1 (0.54) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL9724978 | 0.85 | KMT2A (0.52) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL5037571 | 0.85 | MAPK1 (0.63) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL9724786 | 0.84 | DDX3X (0.51) | RAB9AMEN1KMT2AMAPTTP53 | |
| SCHEMBL20124862 | 0.83 | RAB9A (0.51) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL9724833 | 0.82 | LMNA (0.54) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19316158 | 0.82 | NPC1 (0.74) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL9724968 | 0.81 | KMT2A (0.65) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9724950 | 0.81 | ALDH1A1 (0.54) | RAB9ANPC1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |