SCHEMBL9725533

SCHEMBL9725533

CCN(CC)C(=O)n1cnc(SCC=CCl)n1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 1/20 0.32
DPP4 P27487 1/20 0.31
POLB P06746 1/20 0.30
APOBEC3A P31941 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30
MGLL Q99685 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9725531 1.00 TDP1 (0.32) TDP1LMNADPP4POLBAPOBEC3A
SCHEMBL10509749 0.80 NPC1 (0.35) TDP1LMNAPOLBAPOBEC3AAPOBEC3G
SCHEMBL7660067 0.79 LMNA (0.37) TDP1LMNADPP4POLBAPOBEC3A
SCHEMBL9015526 0.77 MAPT (0.33) TDP1LMNAPOLBAPOBEC3AAPOBEC3G
SCHEMBL9851959 0.76 SMN1; SMN2 (0.43) TDP1LMNAALDH1A1SMN1; SMN2
SCHEMBL10509918 0.76 DPP4 (0.35) TDP1LMNADPP4POLBAPOBEC3A
SCHEMBL9491268 0.76 ALDH1A1 (0.40) TDP1LMNADPP4POLBAPOBEC3A
SCHEMBL9851995 0.75 L3MBTL1 (0.50) TDP1LMNAALDH1A1HPGDSMN1; SMN2
SCHEMBL11376134 0.75 DPP4 (0.34) DPP4POLB
SCHEMBL9015529 0.75 NPC1 (0.51) LMNAPOLBMGLLALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4001182-A None JP disclosed
JP-H041182-A SUBSTITUTED CARBAMOYLTRIAZOLE, PREPARATION THEREOF, AND HERBICIDE INCLUDING THE SAME BAYER AG 1992-01-06 JP disclosed
EP-0433804-A1 Substituted carbamoyltriazoles BAYER AG (DE) 1991-06-26 EP disclosed