Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | CCR3 | P51677 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727125 | 0.86 | KDM4E (0.68) | DRD4SIGMAR1MCHR1ACHEKCNH2 | |
| SCHEMBL9727095 | 0.84 | DRD4 (0.72) | DRD4SIGMAR1MCHR1ACHEALDH1A1 | |
| SCHEMBL9872559 | 0.81 | DRD4 (0.78) | DRD4SIGMAR1MCHR1ACHESMN1; SMN2 | |
| SCHEMBL9727116 | 0.79 | MAOB (0.73) | DRD4SIGMAR1MCHR1ACHEKCNH2 | |
| SCHEMBL9727091 | 0.78 | DRD4 (0.70) | DRD4SIGMAR1MCHR1ACHEKCNH2 | |
| SCHEMBL9727049 | 0.77 | MAOB (0.80) | DRD4SIGMAR1MCHR1ACHEKCNH2 | |
| SCHEMBL9852057 | 0.77 | DRD4 (0.67) | DRD4SIGMAR1MCHR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9727102 | 0.77 | SIGMAR1 (0.72) | DRD4SIGMAR1MCHR1KCNH2HRH3 | |
| SCHEMBL5862230 | 0.76 | SIGMAR1 (1.00) | SIGMAR1 | |
| Iodide SCHEMBL9852255 | 0.76 | DRD4 (0.60) | DRD4SIGMAR1MCHR1ACHEKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098915-A | Antiarrhythmia agents | G. D. SEARLE & CO. (US) | 1992-03-24 | — | — | US | claimed |