Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727344 | 0.90 | MAPT (0.42) | PPARGPPARAMAOBCYP3A4ALDH1A1 | |
| SCHEMBL9459542 | 0.77 | MAPT (0.45) | PPARGCYP3A4ALDH1A1LMNAHPGD | |
| SCHEMBL4926944 | 0.74 | CTSS (0.54) | PPARGPPARAPPARDATMAPP | |
| SCHEMBL5796601 | 0.74 | CTSS (0.54) | PPARGPPARAPPARDATMAPP | |
| SCHEMBL5796611 | 0.74 | CTSS (0.54) | PPARGPPARAPPARDATMAPP | |
| SCHEMBL7398409 | 0.73 | CTRB1 (0.51) | PPARGPPARAATMCYP3A4ALDH1A1 | |
| SCHEMBL31565653 | 0.73 | PPARG (0.42) | PPARGPPARAPPARDATMAPP | |
| SCHEMBL31565652 | 0.73 | PPARG (0.42) | PPARGPPARAPPARDATMAPP | |
| SCHEMBL9727172 | 0.72 | NLRP3 (0.48) | PPARACYP3A4ALDH1A1HTT | |
| SCHEMBL9459549 | 0.71 | LMNA (0.40) | PPARGPPARACYP3A4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543892-B1 | N-(MERCAPTOALKYL)UREAS AND CARBAMATES | SCHERING CORP (US) | 1994-11-23 | — | — | EP | disclosed |
| US-5356925-A | For cardiovascular and urogenital disorders | SCHERING CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |