Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 7/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9797182 | 0.87 | AKR1C3 (0.56) | LMNAL3MBTL1TP53AKR1C3 | |
| SCHEMBL9727563 | 0.87 | AKR1C3 (0.56) | LMNAL3MBTL1TP53AKR1C3 | |
| SCHEMBL9727320 | 0.84 | PKM (0.51) | LMNAKDM4EALDH1A1L3MBTL1TP53 | |
| SCHEMBL9350706 | 0.84 | AKR1C3 (0.52) | LMNAALDH1A1L3MBTL1TP53AKR1C3 | |
| SCHEMBL9351906 | 0.84 | AKR1C3 (0.52) | LMNAALDH1A1L3MBTL1TP53AKR1C3 | |
| SCHEMBL9354611 | 0.84 | AKR1C3 (0.52) | LMNAALDH1A1L3MBTL1TP53AKR1C3 | |
| SCHEMBL2836378 | 0.77 | MAPT (0.67) | LMNAKDM4EALDH1A1HTR6AKR1C3 | |
| SCHEMBL31322362 | 0.76 | MAPT (0.65) | LMNAKDM4EALDH1A1HTR6AKR1C3 | |
| SCHEMBL10702282 | 0.75 | MMP2 (0.64) | TP53AKR1C3 | |
| SCHEMBL7383735 | 0.75 | MMP2 (0.64) | LMNAALDH1A1L3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164514-A | Antispasmodics | ROUSSEL UCLAF (FR) | 1992-11-17 | — | — | US | disclosed |
| US-5081130-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1992-01-14 | — | — | US | disclosed |
| US-4990531-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1991-02-05 | — | — | US | disclosed |
| EP-0335758-A2 | Derivatives of 1-arylsulfonyl-2-pyrolidinone, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1989-10-04 | — | — | EP | disclosed |