Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.69 |
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.61 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | CCR3 | P51677 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727092 | 0.81 | DRD4 (0.63) | DRD4UTS2RMCHR1SIGMAR1CCR3 | |
| SCHEMBL9872559 | 0.80 | DRD4 (0.78) | DRD4MCHR1SIGMAR1CCR3 | |
| SCHEMBL9727091 | 0.79 | DRD4 (0.70) | DRD4UTS2RMCHR1SIGMAR1CCR3 | |
| SCHEMBL9852057 | 0.78 | DRD4 (0.67) | DRD4MCHR1SIGMAR1CCR3 | |
| SCHEMBL9727095 | 0.77 | DRD4 (0.72) | DRD4MCHR1SIGMAR1CCR3 | |
| SCHEMBL9727182 | 0.77 | DRD4 (0.64) | DRD4MCHR1SIGMAR1CCR3 | |
| SCHEMBL9727082 | 0.77 | DRD4 (0.64) | DRD4MCHR1SIGMAR1CCR3 | |
| SCHEMBL9727136 | 0.76 | DRD4 (0.67) | DRD4 | |
| SCHEMBL9727102 | 0.76 | SIGMAR1 (0.72) | DRD4MCHR1SIGMAR1CCR3 | |
| SCHEMBL5862230 | 0.76 | SIGMAR1 (1.00) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098915-A | Antiarrhythmia agents | G. D. SEARLE & CO. (US) | 1992-03-24 | — | — | US | claimed |
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |