Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10391664 | 0.70 | HPGD (0.51) | MTNR1BHPGDDRD2DRD4DRD3 | |
| SCHEMBL9727632 | 0.67 | DRD2 (0.39) | DRD2DRD4DRD3ESR1CYP19A1 | |
| SCHEMBL9854748 | 0.67 | MTNR1A (0.49) | MTNR1BHPGDDRD2DRD4DRD3 | |
| SCHEMBL14255248 | 0.64 | MEN1 (0.51) | MTNR1BHPGDMTNR1ALMNAMAPT | |
| SCHEMBL5287776 | 0.62 | KCNA3 (0.73) | HPGDDRD2DRD4DRD3LMNA | |
| SCHEMBL28312915 | 0.61 | DRD2 (0.70) | HPGDDRD2DRD4DRD3MAPT | |
| SCHEMBL4337645 | 0.60 | DRD2 (0.69) | HPGDDRD2DRD4DRD3LMNA | |
| SCHEMBL5824552 | 0.60 | MAPK1 (0.54) | MTNR1BDRD2DRD4DRD3MTNR1A | |
| SCHEMBL10597796 | 0.59 | MAPK1 (0.68) | MTNR1BDRD2DRD4DRD3MTNR1A | |
| SCHEMBL9854773 | 0.59 | MTNR1B (0.54) | MTNR1BHPGDMTNR1ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091533-A | Treating allergies, cardiovascular disorders, inflammation | MERCK FROSST CANADA, INC. (CA) | 1992-02-25 | — | — | US | disclosed |