Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15079871 | 0.82 | MAPT (0.51) | LMNAGAADRD2DRD4DRD3 | |
| SCHEMBL15079796 | 0.81 | MAPK1 (0.50) | MTNR1AMTNR1BLMNATSHRNPC1 | |
| SCHEMBL8686118 | 0.81 | TDP1 (0.56) | MTNR1AMTNR1BLMNAGAAPOLB | |
| SCHEMBL7736570 | 0.80 | LMNA (0.47) | MTNR1AMTNR1BLMNAGAAPOLB | |
| SCHEMBL9854724 | 0.78 | KCNA3 (0.52) | DRD2DRD4DRD3NPC1RAB9A | |
| SCHEMBL9854773 | 0.77 | MTNR1B (0.54) | MTNR1AMTNR1BLMNAHPGDNPC1 | |
| SCHEMBL10366349 | 0.76 | MTNR1A (0.56) | MTNR1AMTNR1BLMNAGAAPOLB | |
| SCHEMBL28863771 | 0.76 | MTNR1A (0.56) | MTNR1AMTNR1BLMNAGAAPOLB | |
| SCHEMBL14131212 | 0.76 | MTNR1A (0.52) | MTNR1AMTNR1BLMNAGAAPOLB | |
| SCHEMBL15079427 | 0.76 | LTA4H (0.53) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428423-A2 | Aryloxy alkyl benzenes, processes for their preparation and pharmaceutical compositions containing them | LIPHA S.A. (FR) | 1991-05-22 | — | — | EP | claimed |
| JP-3255043-A | — | — | None | — | — | JP | disclosed |
| JP-H03255043-A | NOVEL ARYLOXYALKYLBENZENE, ITS PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LIPHA (LYON IND PHARMACEUT) | 1991-11-13 | — | — | JP | disclosed |
| EP-0428423-A2 | Aryloxy alkyl benzenes, processes for their preparation and pharmaceutical compositions containing them | LIPHA S.A. (FR) | 1991-05-22 | — | — | EP | disclosed |