Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727632 | 0.83 | DRD2 (0.39) | ESR1CYP19A1ESR2MEN1KMT2A | |
| SCHEMBL9727495 | 0.76 | ALDH1A1 (0.43) | ESR1ESR2CALM1MEN1KMT2A | |
| SCHEMBL9727793 | 0.69 | ESR1 (0.44) | ESR1CYP19A1ESR2IGF1RALOX15 | |
| SCHEMBL25328659 | 0.65 | ESR1 (0.69) | ESR1CYP19A1ESR2IGF1RALOX15 | |
| SCHEMBL5253951 | 0.63 | TAAR1 (0.59) | CALM1KMT2ACNR1FPR2 | |
| SCHEMBL8702849 | 0.62 | IGF1R (0.61) | ESR1CYP19A1ESR2IGF1RALOX15 | |
| SCHEMBL4254058 | 0.62 | CALM1 (0.72) | IGF1RALOX15CALM1L3MBTL1 | |
| Broussonin A SCHEMBL774802 | 0.61 | ESR1 (1.00) | ESR1CYP19A1ESR2IGF1RALOX15 | |
| SCHEMBL5252007 | 0.61 | CALM1 (0.60) | IGF1RALOX15CALM1L3MBTL1 | |
| SCHEMBL17400406 | 0.60 | CALM1 (0.69) | IGF1RALOX15CALM1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091533-A | Treating allergies, cardiovascular disorders, inflammation | MERCK FROSST CANADA, INC. (CA) | 1992-02-25 | — | — | US | disclosed |
| EP-0447189-A1 | 5-Hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors | MERCK FROSST CANADA INC. (CA) | 1991-09-18 | — | — | EP | disclosed |