Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728204 | 1.00 | ALDH1A1 (0.35) | ALDH1A1POLBDPP7KDM4EDPP8 | |
| SCHEMBL9728155 | 0.83 | PKM (0.45) | HTTCTSS | |
| SCHEMBL9728206 | 0.78 | HTT (0.36) | ALDH1A1POLBDPP7KDM4EDPP8 | |
| SCHEMBL1328597 | 0.74 | SIRT6 (0.44) | DPP7DPP8DPP9 | |
| SCHEMBL1661759 | 0.74 | SIRT6 (0.44) | DPP7DPP8DPP9 | |
| SCHEMBL8635913 | 0.72 | CTSS (0.44) | ALDH1A1MEN1KMT2ATDP1CTSS | |
| SCHEMBL28335157 | 0.72 | GSR (0.44) | ALDH1A1DPP7DPP8DPP9MEN1 | |
| SCHEMBL27849229 | 0.71 | DPP8 (0.37) | DPP7DPP8DPP9DPP4 | |
| SCHEMBL5155641 | 0.71 | GSR (0.38) | DPP7DPP8DPP9 | |
| SCHEMBL5494838 | 0.71 | GSR (0.38) | DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | claimed |