Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728783 | 0.90 | KDM4E (0.46) | MAOAKDM4EALDH1A1GLAGAA | |
| Hydrochloric Acid SCHEMBL9728481 | 0.80 | SIGMAR1 (0.46) | KCNH2DRD2 | |
| SCHEMBL9729054 | 0.79 | RAD52 (0.40) | KDM4EALDH1A1GAAMAPTHPGD | |
| Hydrochloric Acid SCHEMBL9729647 | 0.74 | CHRM1 (0.44) | — | |
| SCHEMBL9729439 | 0.73 | MAOA (0.39) | MAOAKDM4EALDH1A1GLAGAA | |
| SCHEMBL1852196 | 0.68 | MYC (0.61) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL9728514 | 0.62 | HTR6 (0.36) | DRD2 | |
| SCHEMBL8804098 | 0.62 | MAOA (0.67) | MAOAKCNH2KCNJ1 | |
| SCHEMBL1848508 | 0.61 | MYC (0.43) | KDM4EALDH1A1MAPTMYCWDR5 | |
| SCHEMBL1849138 | 0.60 | MYC (0.43) | KDM4EALDH1A1MAPTMYCWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128340-A | Thiazole derivatives | AKZO N.V. (NL) | 1992-07-07 | — | — | US | disclosed |
| EP-0368384-A1 | Thiazole derivatives | AKZO N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |