Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728276 | 0.90 | MAOA (0.39) | KDM4EMEN1ALDH1A1GLAGAA | |
| Hydrochloric Acid SCHEMBL9728481 | 0.85 | SIGMAR1 (0.46) | — | |
| SCHEMBL9729439 | 0.84 | MAOA (0.39) | KDM4EMEN1ALDH1A1GLAGAA | |
| SCHEMBL9728560 | 0.81 | — | — | |
| SCHEMBL9729054 | 0.81 | RAD52 (0.40) | KDM4EMEN1ALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL9729647 | 0.76 | CHRM1 (0.44) | CHRM1 | |
| SCHEMBL9451990 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2ATAAR1 | |
| SCHEMBL9728485 | 0.73 | DRD2 (0.43) | MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL9728509 | 0.69 | THRB (0.39) | — | |
| SCHEMBL1449744 | 0.66 | CDC7 (0.58) | KDM4EALDH1A1GLAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128340-A | Thiazole derivatives | AKZO N.V. (NL) | 1992-07-07 | — | — | US | disclosed |
| EP-0368384-A1 | Thiazole derivatives | AKZO N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |