Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728272 | 0.91 | RAB9A (0.56) | RAB9ANPC1RXFP1PDE11APDE10A | |
| SCHEMBL9728142 | 0.87 | MEN1 (0.56) | RAB9ANPC1KDM4EHSD17B10MEN1 | |
| SCHEMBL9729063 | 0.87 | MAPK1 (0.57) | RAB9ANPC1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9728332 | 0.82 | MAPT (0.52) | RAB9ANPC1RXFP1PDE11APDE10A | |
| SCHEMBL29510945 | 0.81 | RAB9A (1.00) | RAB9ANPC1RXFP1PDE11APDE10A | |
| SCHEMBL14773948 | 0.81 | RAB9A (1.00) | RAB9ANPC1RXFP1PDE11APDE10A | |
| SCHEMBL9728467 | 0.80 | RAB9A (0.72) | RAB9ANPC1PDE11APDE10AKDM4E | |
| SCHEMBL7224007 | 0.77 | EGFR (0.50) | RAB9ANPC1KDM4EHSD17B10MEN1 | |
| SCHEMBL7217219 | 0.77 | L3MBTL1 (0.54) | RXFP1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL17916715 | 0.76 | RAB9A (0.89) | RAB9ANPC1RXFP1PDE11APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | claimed |
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |