Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAN2A1 | Q16706 | 2/20 | 0.48 |
| ▸ | MAN1B1 | Q9UKM7 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729131 | 0.96 | HPGD (0.55) | HPGDCYP3A4CYP2D6CYP2C9PKM | |
| SCHEMBL25374756 | 0.81 | HPGD (0.45) | HPGDCYP3A4CYP2D6CYP2C9PKM | |
| SCHEMBL6893034 | 0.80 | HPGD (0.53) | HPGDCYP3A4CYP2D6CYP2C9PKM | |
| SCHEMBL24724282 | 0.77 | HPGD (0.50) | HPGDCYP3A4CYP2D6CYP2C9PKM | |
| SCHEMBL9729453 | 0.72 | HPGD (0.56) | HPGDCYP3A4CYP2D6CYP2C9PKM | |
| SCHEMBL29706732 | 0.71 | HPGD (0.51) | HPGDCYP3A4CYP2D6CYP2C9PKM | |
| SCHEMBL20925407 | 0.70 | MGLL (0.46) | HPGDCYP3A4CYP2D6CYP2C9PKM | |
| SCHEMBL20925523 | 0.70 | MGLL (0.46) | HPGDCYP3A4CYP2D6CYP2C9PKM | |
| SCHEMBL9684492 | 0.70 | KCNH3 (0.62) | HPGDCYP3A4CYP2D6CYP2C9PKM | |
| SCHEMBL22716559 | 0.69 | ALDH1A1 (0.58) | HPGDPKMALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171753-A | Derivatives of 2-amino-1-phenylethanol having antiulcer activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-12-15 | — | — | US | disclosed |