Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695945 | 0.78 | ALOX5 (0.74) | ALOX5MTNR1A | |
| SCHEMBL9729641 | 0.76 | ALOX5 (1.00) | ALOX5 | |
| Formamide SCHEMBL9729847 | 0.75 | MTNR1A (0.57) | MTNR1ATP53 | |
| SCHEMBL9729564 | 0.74 | ALOX5 (0.46) | ALOX5MTNR1A | |
| SCHEMBL4100146 | 0.74 | MTNR1A (0.50) | MTNR1A | |
| SCHEMBL24440178 | 0.72 | TP53 (0.51) | MTNR1ATP53 | |
| SCHEMBL1519319 | 0.72 | TP53 (0.51) | MTNR1ATP53 | |
| SCHEMBL29633457 | 0.72 | TP53 (0.51) | MTNR1ATP53 | |
| SCHEMBL9729621 | 0.72 | HTR1A (0.47) | ALOX5 | |
| SCHEMBL9730076 | 0.72 | ALOX5 (0.71) | ALOX5MTNR1ALTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |