Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.71 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729641 | 0.83 | ALOX5 (1.00) | ALOX5 | |
| Formamide SCHEMBL9729549 | 0.74 | MTNR1A (0.45) | ALOX5ITGB3ITGA2BLTB4RLTB4R2 | |
| SCHEMBL9729845 | 0.72 | ALOX5 (0.62) | ALOX5LTB4RLTB4R2MTNR1A | |
| SCHEMBL9730306 | 0.72 | ALOX5 (0.80) | ALOX5MTNR1A | |
| SCHEMBL9695903 | 0.65 | ALOX5 (1.00) | ALOX5MTNR1A | |
| SCHEMBL11453851 | 0.65 | SMN1; SMN2 (0.50) | HRH3 | |
| SCHEMBL6554194 | 0.64 | ITGB3 (0.57) | ALOX5ITGB3ITGA2BLTB4RLTB4R2 | |
| SCHEMBL9382006 | 0.64 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL9382003 | 0.64 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL6554201 | 0.64 | ITGB3 (0.57) | ALOX5ITGB3ITGA2BLTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |