Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.37 |
| ▸ | HTR3B | O95264 | 2/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.36 |
| ▸ | BCL2 | P10415 | 3/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CD44 | P16070 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681702 | 0.82 | MTNR1A (0.41) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Cadaverine Tartrate SCHEMBL7429503 | 0.77 | MTNR1A (0.37) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL8962729 | 0.76 | HTR3A (0.46) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL9730401 | 0.73 | HTR3A (0.38) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7267047 | 0.73 | HTR3A (0.66) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Fumaric Acid SCHEMBL7273886 | 0.72 | HTR3E (0.42) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Maleic Acid SCHEMBL7273875 | 0.72 | HTR3E (0.42) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL19779451 | 0.70 | MCL1 (0.45) | MCL1BCL2PARP1 | |
| SCHEMBL25600150 | 0.70 | MCL1 (0.52) | MCL1BCL2PARP1 | |
| SCHEMBL6325566 | 0.67 | MCL1 (0.43) | MCL1BCL2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102901-A | 5-hydroxytrypamine receptor antaonists | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-04-07 | — | — | US | disclosed |