Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024469 | 0.80 | PKM (0.38) | PKMSMN1; SMN2GPR183ALDH1A1MAPT | |
| SCHEMBL9024104 | 0.75 | PKM (0.39) | PKMSMN1; SMN2GPR183ALDH1A1MAPT | |
| SCHEMBL9024101 | 0.75 | PKM (0.39) | PKMSMN1; SMN2GPR183ALDH1A1MAPT | |
| SCHEMBL9750874 | 0.73 | HMGCR (0.41) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9025069 | 0.69 | HMGCR (0.57) | ALDH1A1PTGS2CYP3A4CYP2C9 | |
| SCHEMBL9025064 | 0.69 | HMGCR (0.57) | ALDH1A1PTGS2CYP3A4CYP2C9 | |
| SCHEMBL9750803 | 0.68 | HMGCR (0.49) | POLB | |
| SCHEMBL9024600 | 0.67 | HMGCR (0.43) | PKMGPR183KMT2A | |
| SCHEMBL9024612 | 0.67 | HMGCR (0.43) | PKMGPR183KMT2A | |
| SCHEMBL9025301 | 0.65 | GAA (0.34) | ALDH1A1KDM4EPTGS2PTGS1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128366-A | Enzyme inhibitors, anticholesterol | SHINOGI & CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |