Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738194 | 0.88 | KMT2A (0.42) | KMT2AMEN1DRD4GRM2ALDH1A1 | |
| SCHEMBL9734083 | 0.87 | ALDH1A1 (0.43) | KMT2AMEN1DRD4GRM2ALDH1A1 | |
| SCHEMBL9733292 | 0.86 | MEN1 (0.45) | KMT2AMEN1ALDH1A1HIF1ARXFP1 | |
| SCHEMBL9734017 | 0.82 | ALDH1A1 (0.48) | KMT2AMEN1GRM2ALDH1A1L3MBTL1 | |
| SCHEMBL9734920 | 0.81 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1L3MBTL1APLNR | |
| SCHEMBL9734163 | 0.79 | HIF1A (0.48) | KMT2AMEN1ALDH1A1HIF1A | |
| SCHEMBL9734943 | 0.77 | HIF1A (0.44) | KMT2AMEN1DRD4ALDH1A1HIF1A | |
| SCHEMBL9733634 | 0.77 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1HIF1ASMN1; SMN2 | |
| SCHEMBL9733469 | 0.77 | MAPT (0.44) | KMT2AMEN1ALDH1A1L3MBTL1HIF1A | |
| SCHEMBL9733484 | 0.74 | MEN1 (0.48) | KMT2AMEN1ALDH1A1HIF1ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |