Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734163 | 0.90 | HIF1A (0.48) | ALDH1A1KMT2AMEN1HIF1AIDO1 | |
| SCHEMBL9734943 | 0.87 | HIF1A (0.44) | ALDH1A1SMN1; SMN2KMT2AMEN1HIF1A | |
| SCHEMBL9733469 | 0.87 | MAPT (0.44) | ALDH1A1KMT2AMEN1HIF1APKM | |
| SCHEMBL9733389 | 0.84 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KMT2AMEN1HIF1A | |
| SCHEMBL9737918 | 0.82 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2HIF1APKMMAPT | |
| SCHEMBL9733292 | 0.82 | MEN1 (0.45) | ALDH1A1SMN1; SMN2KMT2AMEN1HIF1A | |
| SCHEMBL9733574 | 0.82 | KMT2A (0.45) | ALDH1A1SMN1; SMN2KMT2AMEN1HIF1A | |
| SCHEMBL9733634 | 0.80 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KMT2AMEN1HIF1A | |
| SCHEMBL9733819 | 0.80 | L3MBTL1 (0.46) | ALDH1A1PKMMAPTKDM4EHTT | |
| SCHEMBL9734030 | 0.74 | ALDH1A1 (0.36) | ALDH1A1KMT2AMEN1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | claimed |
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |