Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | SLC26A6 | Q9BXS9 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733899 | 0.87 | ALDH1A1 (0.42) | ALDH1A1KDM4EPOLBL3MBTL1KMT2A | |
| SCHEMBL9733669 | 0.85 | ALDH1A1 (0.48) | ALDH1A1KDM4EL3MBTL1KMT2ANPC1 | |
| SCHEMBL9733462 | 0.81 | GAA (0.48) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL17610978 | 0.76 | GABRA2 (0.46) | ALDH1A1KDM4EPOLBKMT2ANPC1 | |
| SCHEMBL16796453 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBKMT2ANPC1 | |
| SCHEMBL17324405 | 0.74 | KMT2A (0.50) | ALDH1A1KDM4EPOLBL3MBTL1KMT2A | |
| SCHEMBL9734269 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EPOLBL3MBTL1KMT2A | |
| SCHEMBL3587879 | 0.72 | GUCY1A1 (0.52) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL20140279 | 0.72 | KMT2A (0.39) | ALDH1A1KDM4EPOLBL3MBTL1KMT2A | |
| SCHEMBL23153544 | 0.71 | RAB9A (0.51) | ALDH1A1KDM4EL3MBTL1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098922-A | Anticonvulsants | CIBA-GEIGY CORPORATION (US) | 1992-03-24 | — | — | US | disclosed |
| US-5045556-A | Aralkyl-4H-1,2,4-triazole derivatives | CIBA-GEIGY CORPORATION (US) | 1991-09-03 | — | — | US | disclosed |