Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733754 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EMAPK1L3MBTL1 | |
| SCHEMBL9734925 | 0.81 | LMNA (0.43) | ALDH1A1MAPTKDM4EMAPK1L3MBTL1 | |
| SCHEMBL9733899 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4ETDP1L3MBTL1 | |
| SCHEMBL23153544 | 0.71 | RAB9A (0.51) | ALDH1A1MAPTKDM4EL3MBTL1LMNA | |
| SCHEMBL21526021 | 0.71 | SLC26A6 (0.54) | ALDH1A1MAPTKDM4EMAPK1TDP1 | |
| SCHEMBL19779913 | 0.71 | KLKB1 (0.47) | MEN1KMT2A | |
| SCHEMBL513530 | 0.70 | PKM (0.53) | ALDH1A1MAPTKDM4EMAPK1NLRP3 | |
| SCHEMBL15932100 | 0.69 | ACR (0.51) | ALDH1A1MAPTKDM4EMAPK1TDP1 | |
| SCHEMBL29819680 | 0.69 | NPC1 (0.77) | ALDH1A1MAPTKDM4EMAPK1TDP1 | |
| SCHEMBL17318453 | 0.68 | PDE3B (0.52) | ALDH1A1MAPTKDM4EMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098922-A | Anticonvulsants | CIBA-GEIGY CORPORATION (US) | 1992-03-24 | — | — | US | disclosed |
| US-5045556-A | Aralkyl-4H-1,2,4-triazole derivatives | CIBA-GEIGY CORPORATION (US) | 1991-09-03 | — | — | US | disclosed |