Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685900 | 0.88 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL9733117 | 0.85 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL9023153 | 0.85 | LTB4R (0.63) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL29377589 | 0.82 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL1418988 | 0.82 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL28538675 | 0.81 | POLB (0.67) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL28910238 | 0.81 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL28542658 | 0.80 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL28239241 | 0.80 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL28900440 | 0.80 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007829-A1 | INDOLE-3-METHANAMINES USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |