Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | DBH | P09172 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734743 | 0.82 | KDM4E (0.45) | KDM4EMPOSMN1; SMN2GAATMEM97 | |
| SCHEMBL9735255 | 0.80 | KDM4E (0.47) | KDM4EMPOSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL31010040 | 0.76 | ALDH1A1 (0.62) | KDM4ESMN1; SMN2GAAALDH1A1HTT | |
| SCHEMBL10011199 | 0.69 | ALDH1A1 (0.56) | KDM4EGAAALDH1A1HTTTDP1 | |
| SCHEMBL9734499 | 0.69 | GAA (0.69) | KDM4ESMN1; SMN2GAAALDH1A1TDP1 | |
| SCHEMBL9733705 | 0.69 | ALDH1A1 (0.62) | KDM4EMPOSMN1; SMN2SIGMAR1ALDH1A1 | |
| SCHEMBL9734904 | 0.69 | MAPK1 (0.43) | KDM4EMPOGAAALDH1A1TDP1 | |
| SCHEMBL9734929 | 0.68 | KDM4E (0.51) | KDM4EMPOGAAALDH1A1TDP1 | |
| SCHEMBL9733496 | 0.68 | KDM4E (0.47) | KDM4EMPOSMN1; SMN2GAASIGMAR1 | |
| SCHEMBL9734162 | 0.68 | GAA (0.79) | KDM4ESMN1; SMN2GAAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106975-A | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0434185-A2 | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-06-26 | — | — | EP | disclosed |