Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | DBH | P09172 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734151 | 0.82 | KDM4E (0.42) | KDM4EALDH1A1MPOHTTTDP1 | |
| SCHEMBL31010040 | 0.80 | ALDH1A1 (0.62) | KDM4EALDH1A1HTTTDP1GAA | |
| SCHEMBL9734499 | 0.79 | GAA (0.69) | KDM4EALDH1A1TDP1GAASMN1; SMN2 | |
| SCHEMBL9733496 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1MPOHTTTDP1 | |
| SCHEMBL9734929 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1MPOTDP1GAA | |
| SCHEMBL9735255 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1MPOHTTTDP1 | |
| SCHEMBL30334972 | 0.74 | ALDH1A1 (0.64) | KDM4EALDH1A1HTTCHKASMN1; SMN2 | |
| SCHEMBL9733660 | 0.71 | ALDH1A1 (0.79) | KDM4EALDH1A1HTTTDP1GAA | |
| SCHEMBL9734162 | 0.71 | GAA (0.79) | KDM4EALDH1A1TDP1GAASMN1; SMN2 | |
| SCHEMBL9733983 | 0.71 | MAPT (0.65) | KDM4EALDH1A1MPOTDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106975-A | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-04-21 | — | — | US | disclosed |