Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 12/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | PRKACG | P22612 | 1/20 | 0.38 |
| ▸ | PRKACB | P22694 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734635 | 0.85 | SMN1; SMN2 (0.47) | TSHRPKMPKLRHSD11B1LMNA | |
| SCHEMBL9735682 | 0.84 | TSHR (0.49) | TSHRPKMPKLRHSD11B1LMNA | |
| SCHEMBL9735393 | 0.81 | HSD11B1 (0.50) | TSHRPKML3MBTL1HSD11B1LMNA | |
| SCHEMBL9734258 | 0.76 | L3MBTL1 (0.43) | TSHRL3MBTL1HSD11B1LMNA | |
| SCHEMBL3466241 | 0.74 | HSD11B1 (0.51) | PKMPKLRHSD11B1 | |
| SCHEMBL3468056 | 0.72 | HSD11B1 (0.49) | HSD11B1 | |
| SCHEMBL29779559 | 0.70 | PKM (0.58) | TSHRPKMPKLRL3MBTL1LMNA | |
| SCHEMBL3045649 | 0.67 | L3MBTL1 (0.62) | TSHRPKML3MBTL1LMNA | |
| SCHEMBL29432528 | 0.67 | PKM (0.54) | TSHRPKMPKLRL3MBTL1KDM4E | |
| SCHEMBL3636698 | 0.67 | L3MBTL1 (0.42) | TSHRL3MBTL1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137886-A | Agriculture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-08-11 | — | — | US | disclosed |
| EP-0433001-A1 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-19 | — | — | EP | disclosed |