Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 12/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735650 | 0.89 | HSD11B1 (0.43) | HSD11B1LMNATSHRSMN1; SMN2 | |
| SCHEMBL9734509 | 0.87 | HSD11B1 (0.42) | HSD11B1LMNATSHRSMN1; SMN2 | |
| SCHEMBL9734149 | 0.86 | TSHR (0.42) | HSD11B1LMNATSHRSMN1; SMN2 | |
| SCHEMBL9724526 | 0.84 | HSD11B1 (0.46) | L3MBTL1HSD11B1LMNATSHRSMN1; SMN2 | |
| SCHEMBL9734308 | 0.76 | TSHR (0.41) | L3MBTL1HSD11B1LMNATSHR | |
| SCHEMBL9734248 | 0.76 | CA1 (0.38) | HSD11B1 | |
| SCHEMBL9865854 | 0.72 | HCAR1 (0.39) | LMNASMN1; SMN2 | |
| SCHEMBL9865677 | 0.71 | HCAR1 (0.36) | — | |
| SCHEMBL9866318 | 0.69 | ALDH1A1 (0.36) | L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL10745662 | 0.69 | TXNRD1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137886-A | Agriculture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-08-11 | — | — | US | claimed |
| US-5137886-A | Agriculture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-08-11 | — | — | US | disclosed |
| EP-0433001-A1 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-19 | — | — | EP | disclosed |