Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756844 | 0.97 | ALDH1A1 (0.57) | ALDH1A1TDP1KDM4ECALM1TSHR | |
| Bromide SCHEMBL995842 | 0.94 | ALDH1A1 (0.55) | ALDH1A1TDP1KDM4ECALM1TSHR | |
| Fluoride Ion SCHEMBL7789157 | 0.94 | ALDH1A1 (0.55) | ALDH1A1TDP1KDM4ECALM1TSHR | |
| Iodide SCHEMBL5085346 | 0.94 | ALDH1A1 (0.55) | ALDH1A1TDP1KDM4ECALM1TSHR | |
| Hydrochloric Acid SCHEMBL1937107 | 0.94 | ALDH1A1 (0.62) | ALDH1A1TDP1KDM4ECALM1TSHR | |
| SCHEMBL7640984 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TDP1KDM4ECALM1TSHR | |
| SCHEMBL7641909 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TDP1KDM4ECALM1TSHR | |
| SCHEMBL6043431 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TDP1KDM4ECALM1TSHR | |
| SCHEMBL7642773 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TDP1KDM4ECALM1TSHR | |
| Water SCHEMBL8528285 | 0.84 | KDM4E (0.52) | ALDH1A1TDP1KDM4ETP53DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114453003-B | Aromatization catalyst and activity recovery method and application thereof | 中国石油化工股份有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-114453003-A | Aromatization catalyst and activity recovery method and application thereof | 中国石油化工股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| US-20090084406-A1 | Composition for stripping and stripping method | SAMSUNG ELECTRONICS CO., LTD. | 2009-04-02 | — | — | US | claimed |
| CN-101398639-A | Composition for stripping and stripping method | SAMSUNG ELECTRONICS CO LTD (KR) | 2009-04-01 | — | — | CN | claimed |
| US-12599937-B2 | Water-based, high-efficiency chemical reagent for substrate surface particle removal | APPLIED MATERIALS, INC. (US) | 2026-04-14 | — | — | US | disclosed |
| US-12481218-B2 | Treatment liquid, method for washing substrate, and method for removing resist | FUJIFILM CORPORATION (JP) | 2025-11-25 | — | — | US | disclosed |
| US-12386265-B2 | Pattern forming method and method for manufacturing electronic device | FUJIFILM CORPORATION (JP) | 2025-08-12 | — | — | US | disclosed |
| US-20250235900-A1 | WATER-BASED, HIGH-EFFICIENCY CHEMICAL REAGENT FOR SUBSTRATE SURFACE PARTICLE REMOVAL | APPLIED MATERIALS, INC. | 2025-07-24 | — | — | US | disclosed |
| US-12276915-B2 | Treatment liquid and treatment method | FUJIFILM CORPORATION (JP) | 2025-04-15 | — | — | US | disclosed |
| US-12097996-B2 | Container, method for manufacturing container, and chemical liquid storage body | FUJIFILM CORPORATION (JP) | 2024-09-24 | — | — | US | disclosed |
| US-20240295822-A1 | PATTERN FORMING METHOD AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE | FUJIFILM CORPORATION (JP) | 2024-09-05 | — | — | US | disclosed |
| US-20240231237-A9 | TREATMENT LIQUID, METHOD FOR WASHING SUBSTRATE, AND METHOD FOR REMOVING RESIST | FUJIFILM CORPORATION (JP) | 2024-07-11 | — | — | US | disclosed |
| US-20060014929-A9 | Liquid phase peptide synthesis of KL-4 pulmonary surfactant | ABDEL-MAGID AHMED F | 2006-01-19 | — | — | US | disclosed |
| US-6492490-B1 | COUPLING POLYPEPTIDE FRAGMENTS HAVING 8-25 AMINO ACID RESIDUES BY REACTING SAID FRAGMENTS WITH A SUITABLE PEPTIDE COUPLING AGENT IN THE PRESENCE OF A TETRAALKYLAMMONIUM HALIDE AS A SOLUBILIZING AGENT | ORTHO PHARMACEUTICAL CORPORATION | 2002-12-10 | — | — | US | disclosed |
| US-20020147302-A1 | Liquid phase peptide synthesis of KL-4 pulmonary surfactant | ABDEL-MAGID AHMED F (US) | 2002-10-10 | — | — | US | disclosed |
| US-6013764-A | PRODUCING SYNTHETIC LUNG PROTEIN; REACTING 3 AND 5 RESIDUE PEPTIDES REPEATEDLY FORMING 21 PEPTIDE LUNG PROTEIN; FOR THE TREATMENT OF ADULT AND NEONATAL RESPIRATORY DISTRESS SYNDROME | ORTHO PHARMACEUTICAL CORP. (US) | 2000-01-11 | — | — | US | disclosed |
| WO-1998002461-A2 | LIQUID PHASE PEPTIDE SYNTHESES OF KL-4 PULMONARY SURFACTANT | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-01-22 | — | — | WO | disclosed |
| US-4656239-A | Process for the preparation of phenol formaldehyde resole resins | PLASTICS ENGINEERING COMPANY (US) | 1987-04-07 | — | — | US | disclosed |
| EP-0029409-B1 | PROCESS FOR PREPARING 5-CYANO-5H-DIBENZ(B,F)AZEPINE AND 5H-DIBENZ(B,F)AZEPINE-5-CARBOXAMIDE | CIBA-GEIGY AG (CH) | 1984-08-15 | — | — | EP | disclosed |
| EP-0029409-A1 | Process for preparing 5-cyano-5H-dibenz(b,f)azepine and 5H-dibenz(b,f)azepine-5-carboxamide | CIBA-GEIGY AG (CH) | 1981-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014929-A9 | Liquid phase peptide synthesis of KL-4 pulmonary surfactant | KLK4, KLK14, SURF4 | ALDH1A1 4009/4885TDP1 3878/4885KDM4E 1332/4885 |
| US-20020147302-A1 | Liquid phase peptide synthesis of KL-4 pulmonary surfactant | KLK4, KLK14, SURF4 | ALDH1A1 4411/4885TDP1 3523/4885KDM4E 1090/4885 |
| US-12599937-B2 | Water-based, high-efficiency chemical reagent for substrate surface particle removal | STUB1, CD2, EPCAM | ALDH1A1 528/4885TDP1 1657/4885KDM4E 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.