Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735247 | 0.84 | ABCC9 (0.34) | ALDH1A1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9735600 | 0.82 | ABCC9 (0.51) | ALDH1A1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9735452 | 0.82 | NR1H4 (0.35) | ALDH1A1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9736903 | 0.81 | OPRD1 (0.34) | ALOX15HSD17B10OPRD1KDM4EMAPT | |
| SCHEMBL9736829 | 0.77 | ABCC9 (0.52) | ALOX15HSD17B10ALDH1A1OPRD1HPGD | |
| SCHEMBL9736662 | 0.74 | DRD3 (0.34) | ALDH1A1OPRD1KDM4E | |
| SCHEMBL9735900 | 0.73 | OPRD1 (0.34) | ALOX15HSD17B10ALDH1A1OPRD1HPGD | |
| SCHEMBL9735947 | 0.73 | ABCC9 (0.39) | ALOX15HSD17B10ALDH1A1HPGDABCC9 | |
| SCHEMBL10913242 | 0.71 | ABCC9 (0.65) | ALOX15HSD17B10ALDH1A1HPGDABCC9 | |
| SCHEMBL10913246 | 0.71 | ABCC9 (0.65) | ALOX15HSD17B10ALDH1A1HPGDABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |