Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197783 | 0.83 | ABCB1 (0.34) | DRD3BACE1MEN1KMT2A | |
| SCHEMBL9735367 | 0.74 | ALOX15 (0.38) | ALDH1A1KDM4EOPRD1 | |
| SCHEMBL9198396 | 0.73 | ABCC9 (0.39) | DRD3 | |
| SCHEMBL9735028 | 0.71 | ABCC9 (0.37) | DRD3BACE1 | |
| SCHEMBL9735829 | 0.70 | ADAM10 (0.38) | GAA | |
| SCHEMBL9738250 | 0.68 | OPRM1 (0.36) | DRD3OPRD1TSHR | |
| SCHEMBL9734831 | 0.68 | ALOX5 (0.37) | ALDH1A1KDM4EOPRD1TSHR | |
| SCHEMBL9735247 | 0.67 | ABCC9 (0.34) | BACE1ALDH1A1MEN1KMT2A | |
| SCHEMBL9735244 | 0.64 | LMNA (0.36) | ALDH1A1KDM4EGAATSHR | |
| SCHEMBL9737531 | 0.64 | ABCC9 (0.40) | ALDH1A1KDM4EMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |