Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735458 | 0.85 | NR1H4 (0.39) | POLBKDM4EMAPTMALT1MEN1 | |
| SCHEMBL9735603 | 0.85 | PDE4A (0.44) | CHEK1MALT1PDE4APDE4BPDE4C | |
| SCHEMBL9735371 | 0.84 | ALDH1A1 (0.37) | POLBNPSR1KDM4EMAPTTSHR | |
| SCHEMBL9737951 | 0.80 | PTGER1 (0.34) | POLBNPSR1KDM4EMAPTMALT1 | |
| SCHEMBL9736934 | 0.76 | NPSR1 (0.33) | NPSR1KDM4EMAPT | |
| SCHEMBL9588069 | 0.72 | CA1 (0.38) | CHEK1MALT1HSD17B10MEN1TSHR | |
| SCHEMBL9587860 | 0.72 | CA1 (0.38) | CHEK1MALT1HSD17B10MEN1TSHR | |
| SCHEMBL9735577 | 0.72 | NPSR1 (0.33) | NPSR1KDM4EMAPTMALT1PBRM1 | |
| SCHEMBL9846729 | 0.71 | BACE1 (0.37) | POLBMALT1HSD17B10CTSDBACE1 | |
| SCHEMBL9737580 | 0.70 | SMN1; SMN2 (0.35) | POLBKDM4EMALT1PTGER1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |