Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090676 | 0.86 | PDE4A (0.35) | LMNAKDM4ENPC1RAB9AABCB1 | |
| SCHEMBL9735503 | 0.82 | ALOX5 (0.35) | LMNAKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL9735525 | 0.80 | KDM4E (0.33) | LMNAKDM4ENPC1RAB9AABCB1 | |
| SCHEMBL9735734 | 0.78 | MALT1 (0.35) | LMNAKDM4EABCB1PDE4APDE4B | |
| SCHEMBL9733219 | 0.74 | LMNA (0.32) | LMNAKDM4ENPC1RAB9AABCB1 | |
| SCHEMBL9372031 | 0.73 | KDM4E (0.33) | LMNAKDM4ENPC1RAB9AABCB1 | |
| SCHEMBL9735910 | 0.71 | ABCC9 (0.42) | LMNAKDM4EABCB1 | |
| SCHEMBL9737765 | 0.70 | ABCB1 (0.38) | KDM4EABCB1 | |
| SCHEMBL9194883 | 0.68 | PDE4A (0.36) | ABCB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9735603 | 0.67 | PDE4A (0.44) | LMNAABCB1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |