Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | HAT1 | O14929 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735739 | 0.77 | OPRM1 (0.37) | OPRM1MMEMDM2HAT1EP300 | |
| SCHEMBL9736562 | 0.77 | MDM2 (0.44) | MDM2MAPK1L3MBTL1LMNAHPGD | |
| SCHEMBL26065 | 0.76 | MDM2 (0.68) | MDM2L3MBTL1LMNA | |
| SCHEMBL9736504 | 0.76 | OPRM1 (0.40) | OPRM1MMEHAT1EP300MAPK1 | |
| SCHEMBL3470504 | 0.75 | GRN (0.43) | OPRM1MAPK1L3MBTL1FNTAFNTB | |
| SCHEMBL7544500 | 0.72 | MAPK1 (0.41) | OPRM1MAPK1L3MBTL1FNTAFNTB | |
| SCHEMBL15570529 | 0.72 | SMN1; SMN2 (0.59) | MAPK1L3MBTL1LMNAHPGDHDAC1 | |
| SCHEMBL9737253 | 0.72 | KDM4E (0.53) | MDM2LMNA | |
| SCHEMBL16295829 | 0.71 | ALDH1A1 (0.38) | OPRM1MAPK1L3MBTL1FNTAFNTB | |
| SCHEMBL25353489 | 0.71 | GRIA1 (0.49) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118685-A | Antiarrhythmia agents | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |