SCHEMBL973103

SCHEMBL973103

Cn1cc(C(=O)Nc2ccc(F)cc2Cl)c(C(F)(F)F)n1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.62
POLB P06746 2/20 0.62
ALOX15 P16050 9/20 0.52
NPSR1 Q6W5P4 1/20 0.46
P2RX7 Q99572 1/20 0.46
STING1 Q86WV6 1/20 0.46
KDM4E B2RXH2 1/20 0.45
GAA P10253 1/20 0.45
GRM4 Q14833 1/20 0.45
DHODH Q02127 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL973582 0.86 LMNA (0.56) LMNAPOLBNPSR1STING1KDM4E
SCHEMBL303303 0.85 LMNA (0.53) LMNAPOLBNPSR1STING1KDM4E
SCHEMBL29445385 0.85 LMNA (0.53) LMNAPOLBNPSR1STING1KDM4E
SCHEMBL1136177 0.85 LMNA (0.64) LMNAPOLBNPSR1STING1
SCHEMBL302660 0.85 LMNA (0.53) LMNAPOLBNPSR1KDM4EGAA
SCHEMBL29505154 0.85 LMNA (0.53) LMNAPOLBNPSR1KDM4EGAA
SCHEMBL13006282 0.85 LMNA (0.55) LMNAPOLBNPSR1
SCHEMBL971566 0.84 POLB (0.66) LMNAPOLBSTING1GAA
SCHEMBL1136137 0.84 LMNA (0.54) LMNAPOLBNPSR1STING1KDM4E
SCHEMBL16618150 0.84 LMNA (0.63) LMNAPOLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2257530-B1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES BAYER CROPSCIENCE AG (DE) 2011-10-12 EP disclosed
US-20110003999-A1 Process for Preparing Substituted Biphenylanilides BAYER CROPSCIENCE AG (DE) 2011-01-06 US disclosed
EP-2093216-A1 Process for preparing substituted biphenylanilides Bayer CropScience AG (DE) 2009-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110003999-A1 Process for Preparing Substituted Biphenylanilides DDT, PAH, THOP1 LMNA 3959/4885POLB 425/4885ALOX15 2438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.