Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 6/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333358 | 0.88 | HTR1A (0.48) | PARP1DRD2HTR7SIGMAR1HTR1A | |
| SCHEMBL7335487 | 0.87 | SIGMAR1 (0.47) | PARP1DRD2DRD3HTR7SIGMAR1 | |
| SCHEMBL9372501 | 0.84 | SIGMAR1 (0.52) | PARP1DRD2SIGMAR1HTR1A | |
| SCHEMBL7299309 | 0.82 | SIGMAR1 (0.49) | PARP1PPARGPPARADRD3SIGMAR1 | |
| SCHEMBL7297853 | 0.81 | SIGMAR1 (0.48) | PPARGPPARADRD2HTR7SIGMAR1 | |
| SCHEMBL9371817 | 0.80 | HTR1A (0.56) | DRD2SIGMAR1HTR1A | |
| Maleic Acid SCHEMBL9375437 | 0.80 | SIGMAR1 (0.46) | PARP1DRD3HTR7SIGMAR1HTR1A | |
| Fumaric Acid SCHEMBL9375443 | 0.80 | SIGMAR1 (0.46) | PARP1DRD3HTR7SIGMAR1HTR1A | |
| SCHEMBL7304233 | 0.79 | SIGMAR1 (0.49) | DRD3HTR7SIGMAR1HTR1A | |
| SCHEMBL7304514 | 0.71 | SMN1; SMN2 (0.41) | PARP1PPARGPPARADRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149817-A | Psychotropic agents | SHIONOGI & CO., LTD. (JP) | 1992-09-22 | — | — | US | disclosed |