Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736879 | 0.94 | L3MBTL1 (0.44) | TSHRKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9735234 | 0.83 | KMT2A (0.44) | TSHRKMT2AMEN1LMNAMAPT | |
| SCHEMBL9736151 | 0.79 | LMNA (0.46) | TSHRKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL9876240 | 0.76 | KDM4E (0.38) | TSHRALDH1A1PKMLMNAMAPT | |
| SCHEMBL9736764 | 0.75 | HTT (0.41) | KMT2AMEN1ALDH1A1PKMLMNA | |
| SCHEMBL29015738 | 0.73 | KMT2A (0.54) | TSHRKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL9845735 | 0.73 | GAA (0.40) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9521448 | 0.69 | TSHR (0.46) | TSHRKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL19990771 | 0.69 | MEN1 (0.68) | TSHRKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL19990817 | 0.67 | L3MBTL1 (0.54) | TSHRKMT2AMEN1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173503-A | Derivatives of N,N-dimethyl-4-phenylalkylenesulfonyl-imidazole -1-sulphonamides; phytopathogenic fungi | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-12-22 | — | — | US | disclosed |
| EP-0432892-A1 | Imidazole fungicides | AgrEvo UK Limited (GB) | 1991-06-19 | — | — | EP | disclosed |