Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735952 | 0.94 | TSHR (0.50) | MAPK1KMT2AMEN1TSHRATM | |
| SCHEMBL9735234 | 0.79 | KMT2A (0.44) | L3MBTL1MAPK1KMT2AMEN1TSHR | |
| SCHEMBL9736151 | 0.78 | LMNA (0.46) | L3MBTL1MAPK1CRHBPCRHR2KMT2A | |
| SCHEMBL9736764 | 0.74 | HTT (0.41) | MAPK1KMT2AMEN1ATMLMNA | |
| SCHEMBL9845735 | 0.71 | GAA (0.40) | MAPK1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL9521448 | 0.68 | TSHR (0.46) | L3MBTL1MAPK1KMT2AMEN1TSHR | |
| SCHEMBL29015738 | 0.66 | KMT2A (0.54) | L3MBTL1KMT2AMEN1TSHRLMNA | |
| SCHEMBL4452372 | 0.66 | CRHBP (0.56) | L3MBTL1CRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL14498366 | 0.65 | L3MBTL1 (0.57) | L3MBTL1MAPK1CRHBPCRHR2KMT2A | |
| SCHEMBL5829479 | 0.65 | KMT2A (0.78) | KMT2AMEN1TSHRATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173503-A | Derivatives of N,N-dimethyl-4-phenylalkylenesulfonyl-imidazole -1-sulphonamides; phytopathogenic fungi | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-12-22 | — | — | US | disclosed |
| EP-0432892-A1 | Imidazole fungicides | AgrEvo UK Limited (GB) | 1991-06-19 | — | — | EP | disclosed |